Research conducted by Cold Spring Harbor Laboratory in New York State, USA has shed light on why the brain produces fewer and fewer neurons with age, resulting in a poorer memory. Associate Professor Grigori Enikolopov, who led the research team, said: “That the production of new neurons declines with age has been well established, but why this happens has been a matter of debate.” He added that adult stem cells in the brain remain dormant for a prolonged time until they are activated. They divide rapidly giving rise to progeny that differentiate into neurons. After that, the stem cells “transform” into non-neural cells. Thus, the study has suggested that the decline in neurons is attributed to the shrinking number of adult stem cells in the brain.